Dr Janet Lye-Keng Wee, BSc, PhD

Research Fellow

Centre for Animal Biotechnology
The University of Melbourne
Vic 3010, Australia
Telephone: + 61 3 834 47369
Facsimile: +61 3 9347 4083
E-mail: jlkwee@unimelb.edu.au

Links

CAB home

Positions held

Present: Post-Doctoral Fellow, Centre for Animal Biotechnology, The University of Melbourne (Australia)
2000-2005: Post-doctoral researcher at the Austin Research Institute (Heidelberg, Australia).  

Janet is the author of 9 articles in refereed journals and is a member of the Transplantation Society of Australia and New Zealand.

Tertiary education

Research interests

• Regulation of immune responses
• Cell signalling
• Infectious diseases

Selected papers

• Mulley WR, Wee JL, Christiansen D, Milland J, Ierino FL and Sandrin MS. (2006) Lentiviral expression of CTLA4Ig inhibits primed xenogeneic lymphocyte proliferation and cytokine responses. Xenotransplantation 13:248-252.
• Wee JL and Jackson DE. (2006) Phosphotyrosine signalling in platelets: Lessons for vascular thrombosis. Current Drug Targets 7:1-9.
• Wee JL and Jackson DE. (2005) The Ig-ITIM superfamily member, PECAM-1 regulates the 'outside-in' signalling properties of integrin aIIb3 in platelets. Blood 106(12):3816-3823.
• Lau LM, Wee JL, Wright MD, Moseley GW, Hogarth PM, Ashman LK, Jackson DE. (2004) The tetraspanin superfamily member CD151 regulates outside-in integrin alphaIIbbeta3 signaling and platelet function. Blood 104(8): 2368-2375.
• Wong MX, Harbour SN, Wee JL, Lau LM, Andrews RK, Jackson DE.(2004) Proteolytic cleavage of platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31) is regulated by a calmodulin-binding motif. FEBS Lett. 568(1-3):70-78.