Dr Vern Bowles, BAgSc, PhD

Senior Research Fellow–Deputy Director of CAB

Centre for Animal Biotechnology
The University of Melbourne
Vic 3010, Australia
Telephone: +61 3 8344 4439
Facsimile: +61 3 9347 4083
E-mail: v.bowles@vet.unimelb.edu.au

Links

CAB home
CAB Cellular Immunology
Hatchtech Pty Ltd

Resume

2001–Present: Director of Hatchtech Pty Ltd and Senior Research Fellow at The Centre for Animal Biotechnology, The University of Melbourne (Australia) investigating novel control strategies against parasites.
1995–2001: Senior Research Fellow at The Centre for Animal Biotechnology, The University of Melbourne (Australia) investigating immune responses in sheep induced through vaccination.
1988–1995: Research fellow at The Centre for Animal Biotechnology, The University of Melbourne (Australia) investigating immune responses in sheep to internal and external parasites.
1983–1988: Doctor of Philosophy, La Trobe University, Australia. Thesis: "Proteases of Lucilia cuprina and their role in blowfly infections."
1979–1983: Bachelor of Agricultural Science (Honours), La Trobe University, Australia.

Vern Bowles is author of over 25 articles in refereed journals and is a member of the Australasian Society for Immunology and the Australian Society for Parasitology.

Research Interests

• Novel Drug Targets
• Regulation of immune responses through vaccination
• Delivery technologies for vaccines and therapeutics

 Supervised students

• Dr Anna Young (PhD, 1996) Lucilia cuprina: secreted products involved in egg hatch and wound initiation.
• Dr Paul Egan (PhD, 1996) Synthesis and secretion of ovine IL-1b and TNF-a.
• Dr Adam Balic (PhD, 1999) A novel protective antigen for sheep nematode parasites.
• Dr Nunzio Mancuso (PhD, 2000) Designer drugs for the control of flystrike.
• Dr Stuart Barber (PhD, 2005) Controlled drug delivery.

Selected papers

• Bowles, V.M., Meeusen, E.N.T., Young, A.R., Nash, A.D., Andrews, A.E. & Brandon, M.R. (1996) Vaccination of sheep against larvae of the sheep blowfly (Lucilia cuprina). Vaccine 14:1347–1352.
• Nash, A.D., Egan, P.J., Kimpton, W., Elhay, M.J. and Bowles, V.M. (1996). Local cell traffic and cytokine production associated with ectoparasite infection. Vet Immunol Immunopathol 54:269–279.
• Young A, Meeusen E.N.T. and Bowles V.M. (1996). Characterisation of ES products involved in wound initiation by Lucilia cuprina larvae. Int J Parasitol 26:245–252.
• Tellam, R. and Bowles, V.M. (1997). Control of blowfly strike in sheep: Current strategies and future prospects. Invited review. Int J Parasitol. 27:261–273.
• Young, A.R., Mancuso, N. and Bowles, V.M. (1999). Biochemical aspects of egg hatch in endo- and ectoparasites: potential for rational drug design. Invited review. Int J Parasit 29:861–867.
• Meeusen, ENT. Balic, A. and Bowles, V. M. (2005). Cells, cytokines and other molecules associated with rejection of gastrointestinal nematode parasites. Vet Immunol Immunopathol 108(1-2): 121-125